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If a CNS depressant or benzodiazepine are desired inside of a client already on an opioid analgesic: Initiate with a lessen Original dose of the benzodiazepine or other CNS depressant; titrate based on scientific response.Allergies to Ingredients. People who are allergic to any of the subsequent mustn't use buprenorphine/naloxone.Babies born to mom